Since 1946, the Faculty of Pharmaceutical Sciences at UBC has made a lasting difference in the health and well-being of people throughout British Columbia and beyond. UBC Pharm Sci is proud to have shaped the education and expertise of thousands of pharmacists and pharmaceutical scientists whose work has improved patient care and pharmaceutical research across the world. July 14 - August 14, 2018 Course Packages Pharmaceutical Sciences Package A – Making Better Medicines The Discovery of New Medicines “What does it take to find a new drug?” The objective of the course will be to answer this question by introducing the participants to the drug discovery and development process. Specifically, the role of the Pharmaceutical Sciences in the discovery of new medicines will be described. Case studies will be presented by experienced scientists that illustrate challenges that interdisciplinary drug discovery teams must overcome. In addition, participants will have an opportunity to visit the laboratories of a local research organization involved in supporting drug discovery efforts. By taking this course, participants will gain an appreciation of the collaborative work that is required in the search for new therapies. Personalizing Medicines with Genomics and Biotechnology For millennia, we have sought to understand how to treat disease using potions, teas, pills and most recently, genetically engineered cells. Indeed, the use of cutting-edge technology in drug discovery is not new- for example, the most powerful anti-malaria drug was re-discovered in the writings of Ge Hong, a physician who practiced 1700 years ago. Today when one thinks of drug discovery and development, large multibillion dollar pharmaceutical companies come to mind, with their remarkable medications for infections, heart disease and cancer. Despite their effectiveness, these medicines tend to treat all patients as members of one homogeneous population. Recently, next generation DNA sequencing is making the possibility of medicine tailored to an individual a reality. Cancer treatments can now be designed to match your specific DNA, eliminating the trial-and-error approach to treatment. Similarly, DNA sequencing can match your prescriptions to your genome. The integration of DNA sequencing with drug therapy has been a disruptive innovation, bringing the science of “big data” to medicine and pharmacy. In this course we will explore how these and other innovations are revolutionizing healthcare and wellness. Package B – Applied Clinical Pharmacy Adverse Drug Related Events and Drug Interactions In the era of increased attention to overall patient safety, several interventions have been implemented to attempt to reduce medication misadventure in both the community and hospital setting. However, patients continue to experience adverse drug-related events (ADREs) which are associated with significant morbidity and mortality and result in many hospital visits. Drug interactions may lead to an increase or decrease in either beneficial or adverse effects of a drug. Pharmacists must identify, treat, and prevent drug-related problems such as ADREs. Students will explore the mechanisms of drug interactions, and the impact of ADREs in Canada, and discuss the overall burden on the health-care system. Principles of Medication Safety Medication is one of the most common interventions used for treating or managing disease and for alleviating symptoms. When prescribed and used appropriately, drug therapy can markedly contribute to improved patient outcomes. However, despite the best of intentions, medication use can also pose risks to patient safety, increasing morbidity and mortality, and can dramatically increase healthcare costs. Through case studies and practical examples, students will gain an understanding of the medication safety principles and practices used by healthcare providers to reduce and prevent patient safety incidents. Current issues including substances of abuse and drug overdose will be explored.